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1011-601X_2017_30_6

Pakistan Journal of Pharmaceutical Sciences

SYNTHESIS, CHARACTERIZATION AND ANTINOCICEPTIVE ACTIVITIES OF NOVEL 2- (2,4-DICHLOROPHENYL)-4H-CHROMEN-4-ONE

Author: Mohammad Shoaib, Syed Wadood Ali Shah, Shafiullah Shah, Nawaz Khan and Muhammad Naeem Ahmed Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 6 ABSTRACT: A novel flavone derivative has been synthesized in good yield from ketone and aldehyde. The structure has been established by different spectroscopic techniques like 1 H NMR, 13C NMR, IR and elemental analysis. The compound was […]

SYNTHESIS, CHARACTERIZATION AND ANTINOCICEPTIVE ACTIVITIES OF NOVEL 2- (2,4-DICHLOROPHENYL)-4H-CHROMEN-4-ONE Read More »

CHARACTERIZATION OF PATHOGENS INVOLVED IN VENTILATOR ASSOCIATED PNEUMONIA IN SURGICAL AND MEDICAL INTENSIVE CARE UNITS – A SINGLE CENTER EXPERIENCE

Author: Saghir Ahmad1, Nafees Bacha, Jehan Bakht and Jawad Ahmed Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 6 ABSTRACT: In the present study 60 samples were collected from lower respiratory tract of patients suffering from Ventilator Associated Pneumonia (VAP) admitted in surgical and medical Intensive Care Units (ICUs) of Khyber Teaching Hospital, Peshawar, Pakistan. Recovered pathogens were characterized and their

CHARACTERIZATION OF PATHOGENS INVOLVED IN VENTILATOR ASSOCIATED PNEUMONIA IN SURGICAL AND MEDICAL INTENSIVE CARE UNITS – A SINGLE CENTER EXPERIENCE Read More »

GROWTH PATTERNS OF MONOSODIUM URATE MONOHYDRATE (GOUTY AND URINARY) CRYSTALS IN GEL: AN IN VITRO STUDY

Author: Salman Ahmed, Muhammad Mohtasheemul Hasan and Zafar Alam Mahmood Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 6 ABSTRACT: Monosodium urate monohydrate crystals are deposited in peripheral joints causing gout and elicit an intense localized inflammatory attack whereas in collecting ducts and medullary interstitium as a urinary calculi which causes dysuria, nausea and hematuria. The purpose of present study is

GROWTH PATTERNS OF MONOSODIUM URATE MONOHYDRATE (GOUTY AND URINARY) CRYSTALS IN GEL: AN IN VITRO STUDY Read More »

SPONDIAS MOMBIN L. (ANACARDIACEAE) ENHANCES DETOXIFICATION OF HEPATIC AND MACROMOLECULAR OXIDANTS IN ACETAMINOPHEN-INTOXICATED RATS

Author: Sabiu Saheed, Sunmonu Olatunde Taofik, Ajani Emmanuel Oladipo and Ashafa Anofi Omotayo Tom Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 6 ABSTRACT: Oxidative stress is a common pathological condition associated with drug-induced hepatotoxicity. This study investigated Spondias mombin L. aqueous leaf extract on reactive oxygen species and acetaminophen-mediated oxidative onslaught in rats’ hepatocytes. Hepatotoxic rats were orally administered with

SPONDIAS MOMBIN L. (ANACARDIACEAE) ENHANCES DETOXIFICATION OF HEPATIC AND MACROMOLECULAR OXIDANTS IN ACETAMINOPHEN-INTOXICATED RATS Read More »

IN-SILICO IDENTIFICATION AND EVALUATION OF PLANT FLAVONOIDS AS DENGUE NS2B/NS3 PROTEASE INHIBITORS USING MOLECULAR DOCKING AND SIMULATION APPROACH

Author: Muhammad Tahir ul Qamar, Usman Ali Ashfaq, Kishver Tusleem, Arooj Mumtaz, Quratulain Tariq, Alina Goheer and Bilal Ahmed Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 6 ABSTRACT: Dengue infection is prevailing among the people not only from the developing countries but also from the developed countries due to its high morbidity rate around the globe. Hence, due to the

IN-SILICO IDENTIFICATION AND EVALUATION OF PLANT FLAVONOIDS AS DENGUE NS2B/NS3 PROTEASE INHIBITORS USING MOLECULAR DOCKING AND SIMULATION APPROACH Read More »