JatsTech

1011-601X_2017_30_5

Pakistan Journal of Pharmaceutical Sciences

CURCUMIN INHIBITS THE PROLIFERATION AND INDUCES APOPTOSIS IN HT-29 CELL LINES THROUGH A REACTIVE OXYGEN SPECIES (ROS)-DEPENDENT MECHANISM

Author: Jinbo Wang, Lili Qi, Lehe Mei, Zhige Wu Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: Curcumin, a natural pigment extracted from Curcuma longa, has anti-carcinogenic activities in many cancer cell lines. The molecular mechanism of apoptosis induced by curcumin are still unknown. In the current study, we investigated the roles of reactive oxygen species in curcumin stimulated […]

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POTENTIAL OF NIGELLA SATIVA SEED AQUEOUS EXTRACT IN AMELIORATING QUININE-INDUCED THROMBOCYTOPENIA IN RATS

Author: Mubshara Saadia, Saba Rehman, Sehrish Robin, Tahira Ruby, Muhammad Sher, Waseeq Ahmad Siddiqui , Mahmood Ahmad Khan Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: Dengue infection is rapidly spreading in most of the countries of south Asia. It is of utmost importance to explore the plants with “anti-thrombocytopenic activity” the dreadful response of dengue fever. The present

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SERUM LEVELS OF LEPTIN, ZINC AND TRYPTOPHAN WITH OBESITY: A CASE-CONTROL STUDY

Author: Noreen Samad Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: The obesity epidemic has turn into a major health threat worldwide and extensively responsible for the increased incidence of many diseases such as diabetes, cardiovascular disease and certain types of cancer. Excessive food intake along with the insufficient physical exercise is the basic impetus for this development. The

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MODEL DESIGN FOR SCREENING EFFECTIVE ANTIHYPERLIPIDEMIC DRUGS USING ZEBRAFISH SYSTEM

Author: Kan Chen, Chang-qian Wang, Yu-qi Fan, Yu-shui Xie, Zhao-fang Yin, Zuo-jun Xu, Hui-li Zhang, Jia-tian Cao, Yue Wang and Lin Gao Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: The purpose of this paper was to explore a new method for screening lipid-lowering drugs in zebrafish models. The suitable drug concentrations of atorvastatin (ATV), fenofibrate (FEF) and ezetimibe

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EVALUATION OF ARTEMISIA SCOPARIA FOR HEMOSTASIS PROMOTION ACTIVITY

Author: Moniba Sajid, Muhammad Rashid Khan, Naseer Ali Shah, Tayyaba Sher Waris, Tahira Younis, Shafi Ullah, Nadeem Ahmed Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: Excessive hemorrhage through any reasons is a life threatening process. Artemisia scoparia of family Asteraceae has been used in local system of medicine to stop bleeding from wounds and in injuries, antiseptic, in

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