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1011-601X_2017_30_5

Pakistan Journal of Pharmaceutical Sciences

ENHANCEMENT OF ANTI-INFLAMMATORY ACTIVITY OF POLYPHENOLIC FLAVONOID RUTIN BY ENCAPSULATION

Author: Pensak Jantrawut, Rungsinee Phongpradist, Monika Muller, Helmut Viernstein Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: The cellular mechanisms underlying the anti-inflammatory activity of rutin which has been found to have in vivo inhibitory effects merit more evaluation. The effects of rutin and encapsulated-rutin on lipopolysaccharide (LPS)- induced IL-6 secretion, NF-κB expression, as well as protein denaturation were […]

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STABILITY COMPARISON OF TWO DERMAL EMULSIONS CONTAINING HIPPOPHAE RHAMNOIDES L. OIL

Author: Hina Hussain, Muhammad Irfan Masood, Muhammad Naeem Amir, Humaira Majeed Khan Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: Two formulations of multiple emulsion (ME-1 & ME-2) containing Hipophae rhamnoides L. oil were prepared. Along with emulsifiers (Abil EM 90, Synperonic F127), Magnesium and Zinc were used as stabilizer in ME-1 and ME-2 respectively. Both formulations were prepared

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ANTIMICROBIAL AND WOUND HEALING POTENTIAL OF MARHAM-E-AATSHAK (A HERB-O-MINERAL FORMULATION)

Author: Noman Anwar, Kamal YT, Mohd Aftab Ahmad, Shahana Salam, Mohd Asif, Mohd Akhtar, Sayeed Ahmad Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: Marham-e-Aatshak (MA) is a Unani ointment, with wide use for treating chronic and infectious wounds since long time. This study was designed to screen the antimicrobial and wound healing potential of MA to validate the

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ROLE OF GAD PEPTIDES P217 AND P290 IN THE REPAIR OF INS RECEPTOR IN SALIVARY TISSUES OF TYPE 1 DIABETIC MICE

Author: Rodrigo Eduardo da Silva, Nilva de Karla Cervigne, Clovis Antonio Lopes Pinto, Marcelo Rodrigues da Cunha, Fernanda Rojas, Luis Antonio Peroni, Taize Machado Augusto, Evaldo Marchi, Barkat Ali Khan, Eduardo José Caldeira Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is a protein associated with autoimmune diseases, including type-1 diabetes. This

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HEPATOPROTECTIVE ACTIVITY AND PHENOLIC PROFILE OF ZANTHOXYLUM ALATUM ROXB. FRUIT EXTRACT

Author: Syed Mubashar Sabir, Joao Batista Texeira Rocha, Aline Agusti Boligon, Margareth Linde Athayde Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: Zanthoxylum alatum Roxb. (Rutaceae) is a medicinal plant, which abundantly grows in the hilly areas of Pakistan. In the present study, the hepatoprotective activity of the Z. alatum whole fruit was evaluated. The hepatoprotective effect of the

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