JatsTech

1011-601X_2017_30_3

Pakistan Journal of Pharmaceutical Sciences

COMPARATIVE STUDIES ON RABBIT PLASMA LIPID PROFILE FED WITH SILYBUM MARIANUM OIL, SUNFLOWER OIL AND VEGETABLE GHEE

Author: Ghosia Lutfullah, Aziz-Ur-Rahman, Aftab Ahmad, Taufiq Ahmad, Amjad Ali and Jan Alam Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 3 ABSTRACT: Present work is aimed to compare the physicochemical characterization and biochemical effects of oil extracted from Silybum Marianum and Sunflower oil, collected from Peshawar (Pakistan). To investigate the comparative effects on the body weight, organ weight and lipid […]

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EVALUATION OF NEPHROPROTECTIVE ACTIVITY OF MUSA PARADISIACA L. IN GENTAMICIN-INDUCED NEPHROTOXICITY

Author: Khizar Abbas, Ghazala H Rizwani, Hina Zahid and M Imran Qadir Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 3 ABSTRACT: The objective of the study was to investigate the nephroprotective activity of methanolic extract of different morphological parts (bract, flower, trachea and tracheal fluid) of Musa paradisiaca L. (Family: Musaceae) against gentamicin-induced nephrotoxicity in mice. Gentamicin produced significant changes

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IMPACT OF BOVINE AND HUMAN SERUM ALBUMIN ON CURCUMIN IN VITRO ACTIVITY AGAINST STAPHYLOCOCCUS AUREUS

Author: Sin Yeang Teow and Syed Atif Ali Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 3 ABSTRACT: This study evaluated the impact of pH (7.4 and 6.5), bovine serum albumin (BSA), and human serum albumin (HSA) on Curcumin activity against 2 reference, 1 clinical, and 10 environmental strains of Staphylococcus aureus (S. aureus). Minimal inhibitory concentrations (MICs) of Curcumin against

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REPEATED TREATMENT WITH RESERPINE AS A PROGRESSIVE ANIMAL MODEL OF DEPRESSION

Author: Huma Ikram and Darakhshan J Haleem Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 3 ABSTRACT: Treatment-resistant depression is a major health problem worldwide. Restricted validity of the existing animal models of depression along with the need for the study of progressive development of resistance to antidepressants, demands the modeling of a progressive animal model of depression. Present study was

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ANALYSIS OF DESIGNER DRUGS IN HUMAN BLOOD USING GAS CHROMATOGRAPHYMASS SPECTROMETRY

Author: Xueguo Chen and Dan Zhao Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 3 ABSTRACT: A robust gas chromatography-mass spectrometry method was utilized in the qualitative and quantitative analysis of designer drugs in human blood. Designer drugs, including methcathinone, 3, 4- methylenedioxymethcathinone, 4’-methyl-α-pyrrolidinopropiophenone and methylenedioxy-pyrovalerone were simultaneously analyzed by gas chromatography-mass spectrometry. Liquid-liquid small volume extraction was employed in the

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