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1011-601X_2017_30_3

Pakistan Journal of Pharmaceutical Sciences

SYNTHESIS, CHARACTERIZATION AND ENZYME INHIBITORY ACTIVITY OF NEW PYRAZINAMIDE IRON COMPLEXES

Author: Mohsin Ali, Shah Ali Ul Qader, Faiza Shahid, M Saeed Arayne and Majid Mumtaz Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 3 ABSTRACT: The present paper deals with synthesis, characterization and amylase inhibitory activity of pyrazinamide (PYZ) with iron in its both (II) and (III) oxidation states. The synthesized complexes were characterized on the basis of IR, UV, 1H-NMR, […]

SYNTHESIS, CHARACTERIZATION AND ENZYME INHIBITORY ACTIVITY OF NEW PYRAZINAMIDE IRON COMPLEXES Read More »

EVALUATION OF ED50 AND 5Α-REDUCTASE INHIBITOR ACTIVITIES OF SOME THIOPYRIMIDINE, PYRANE, PYRAZOLINE AND THIAZOLOPYRIMIDINE DERIVATIVES

Author: Abd El-Galil E. Amr, Mohamed A. Al-Omar and Mohamed M Abdalla Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 3 ABSTRACT: In this work, twenty-one thiopyrimidine (1-21) candidates containing a pyrane, pyrazoline and thiazolopyrimidine ring screened for their ED50 and 5α-reductase inhibitors comparable to that of Anastrozole as positive drug. Some of the tested product showed moderate 5α-reductase inhibitors with

EVALUATION OF ED50 AND 5Α-REDUCTASE INHIBITOR ACTIVITIES OF SOME THIOPYRIMIDINE, PYRANE, PYRAZOLINE AND THIAZOLOPYRIMIDINE DERIVATIVES Read More »

IDENTIFICATION AND GROWTH OPTIMIZATION OF A MARINE BACILLUS DK1-SA11 HAVING POTENTIAL OF PRODUCING BROAD SPECTRUM ANTIMICROBIAL COMPOUNDS

Author: Muhammad Naseem Khan, Hong Lin, Meng Li, *Jingxue Wang, Zulfiqar Ali Mirani, Seema Ismat Khan, Muhammad Aslam Buzdar,Imran Ali and Khalid Jamil Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 3 ABSTRACT: Control of harmful bacteria in food, aquaculture, pharmaceuticals, agriculture, hospitals and recreation water pools are of great global concern. Marine bacteria are an enormous source of bio-controlling agents.

IDENTIFICATION AND GROWTH OPTIMIZATION OF A MARINE BACILLUS DK1-SA11 HAVING POTENTIAL OF PRODUCING BROAD SPECTRUM ANTIMICROBIAL COMPOUNDS Read More »

IMPACT OF DIFFERENT ORGANIC ACIDS ON SOLUBILITY ENHANCEMENT OF CEFPODXIME PROXETIL IMMEDIATE RELEASE TABLET AND ITS STABILITY STUDIES

Author: Sabahat Jabeen, Fouzia Hassan, Rabia Ismail Yousuf, Muhammad Harris Shoaib, Fozia Israr, Syed Muhammad Farid Hasan, Rehana Saeed and Sadaf Farooqi Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 3 ABSTRACT: Cefpodoxime proxetil is a third generation cephalosporin antibiotic demonstrates pH dependent solubility and is highly soluble only in acidic pH. The purpose of this investigation was to design and

IMPACT OF DIFFERENT ORGANIC ACIDS ON SOLUBILITY ENHANCEMENT OF CEFPODXIME PROXETIL IMMEDIATE RELEASE TABLET AND ITS STABILITY STUDIES Read More »

INFLUENCE OF WATER-SOLUBLE CHANNELING AGENTS ON THE RELEASE OF DICLOFENAC SODIUM FROM IRVINGIA MALAYANA WAX MATRIX TABLETS

Author: Songwut Yotsawimonwat, Suporn Charumanee, Sayam Kaewvichit, Jakkapan Sirithunyalug, Panee Sirisa-ard, Sirivipa Piyamongkol and Kulthawat Siangwong Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 3 ABSTRACT: Irvingia malayana wax (IW) is majorly composed of esters of medium chain fatty acids. Its melting point is low and closed to the body temperature. This study aimed at investigating the potential of IW as

INFLUENCE OF WATER-SOLUBLE CHANNELING AGENTS ON THE RELEASE OF DICLOFENAC SODIUM FROM IRVINGIA MALAYANA WAX MATRIX TABLETS Read More »