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1011-601X_2016_29_6

Pakistan Journal of Pharmaceutical Sciences

ANTIBACTERIAL ACTIVITY OF CRUDE METHANOLIC EXTRACT AND VARIOUS FRACTIONS OF VITEX AGNUS CASTUS AND MYRSINE AFRICANA AGAINST CLINICAL ISOLATES OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS

Author: Bashir Ahmad, Nabia Hafeez, Gulshan Ara, Sadiq Azam, Shumaila Bashir2 and Ibrar Khan Publishing Date: 2016 E-ISSN: 1011-601X Volume 29 Issue 6 ABSTRACT: Staphylococcus aureus is a nosocomial pathogen that resides in the soft tissues causing many diseases. The current study was conducted to determine the prevalence of Methicillin Resistant S. aureus (MRSA) in ear discharge and pus of patients […]

ANTIBACTERIAL ACTIVITY OF CRUDE METHANOLIC EXTRACT AND VARIOUS FRACTIONS OF VITEX AGNUS CASTUS AND MYRSINE AFRICANA AGAINST CLINICAL ISOLATES OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS Read More »

INVESTIGATION OF REPRESSIVE AND ENHANCIVE EFFECTS OF FRUIT EXTRACTS ON THE ACTIVITY OF GLUCOSE-6-PHOPHATASE

Author: Muhammad Zahoor, Muhammad Rasul Jan and Sumaira Naz Publishing Date: 2016 E-ISSN: 1011-601X Volume 29 Issue 6 ABSTRACT: Glucose-6-phosphatase is a key enzyme of glucose metabolic pathways. Deficiency of this enzyme leads to glycogen storage disease. This enzyme also plays a negative role in diabetes mellitus disorder in which the catalytic activity of this enzyme increases. Thus there is need

INVESTIGATION OF REPRESSIVE AND ENHANCIVE EFFECTS OF FRUIT EXTRACTS ON THE ACTIVITY OF GLUCOSE-6-PHOPHATASE Read More »

METHANOLIC EXTRACT OF PEGANUM HARMALA EXHIBIT POTENT ACTIVITY AGAINST ACANTHAMOEBA CASTELLANII CYSTS AND ITS ENCYSTMENT IN VITRO

Author: Hafiz Muhammad Shohaib, Salik Nawaz and Abdul Matin Publishing Date: 2016 E-ISSN: 1011-601X Volume 29 Issue 6 ABSTRACT: Acanthamoeba castellanii is member of free living amoeba that may cause painful sight-threatening keratitis and life threatening encephalitis which involves central nervous system. Treatments for both infections are problematic because of the amoebic cysts resistance to therapeutic agents. Here we evaluated in

METHANOLIC EXTRACT OF PEGANUM HARMALA EXHIBIT POTENT ACTIVITY AGAINST ACANTHAMOEBA CASTELLANII CYSTS AND ITS ENCYSTMENT IN VITRO Read More »

SYNTHESIS, PHYSICOCHEMICAL CHARACTERIZATION AND PHARMACOLOGICAL INVESTIGATION OF INDOLACIN-5-FLUOROURACIL-1-YLMETHYL ESTER

Author: Jing Wang, Mei-Juan Zou, Lei Chen, Yi-Ling Sheng, Xiao-Mian Zhou and Xiang-Rong Zhang Publishing Date: 2016 E-ISSN: 1011-601X Volume 29 Issue 6 ABSTRACT: The objective of this work is to synthesize indolacin-5-fluorouracil-1-ylmethyl ester and the structure was confirmed by means of UV, IR, 1H-NMR, 13C-NMR and mass spectrometry. The physicochemical parameters of melting point, solubility, apparent partition coefficient were investigated.

SYNTHESIS, PHYSICOCHEMICAL CHARACTERIZATION AND PHARMACOLOGICAL INVESTIGATION OF INDOLACIN-5-FLUOROURACIL-1-YLMETHYL ESTER Read More »

CLINICAL STUDY ON THE EFFICACY OF AMOEBEX (CODED HERBAL DRUG) COMPARED WITH METRONIDAZOLE FOR THE TREATMENT OF AMOEBIC DYSENTERY

Author: Syed Muhammad Ali Shah, Khan Usmanghani, Naveed Akhtar, Muhammad Akram, Hafiz Muhammad Asi4 and Muhammad Mohtasheemul HasaN Publishing Date: 2016 E-ISSN: 1011-601X Volume 29 Issue 6 ABSTRACT: Amoebiasisis an infectious disease, which originated with the single-celled parasitic protozoan Entamoeba histolytica. The parasitic amoeba infects the liver and intestine and may cause mild diarrhea and serious dysentery with bloody and mucoid

CLINICAL STUDY ON THE EFFICACY OF AMOEBEX (CODED HERBAL DRUG) COMPARED WITH METRONIDAZOLE FOR THE TREATMENT OF AMOEBIC DYSENTERY Read More »