JatsTech

1011-601X_2016_29_5

Pakistan Journal of Pharmaceutical Sciences

ASTRAGALUS EXTRACT INHIBITS PROLIFERATION BUT ENHANCES APOPTOSIS IN GASTRIC CANCER

Author: Zhengguang Wang, Liuyi Dong, Yinan Zhen, Yanan Wang, Dongjiang Qi, Aman Xu, Xiangling Meng and Weiping Li Publishing Date: 2016 E-ISSN: 1011-601X Volume 29 Issue 5 ABSTRACT: We and others have shown that Astragalus extract (AE) regulates various cellular processes including inflammation and apoptosis. It remains elusive whether and how AE modulates apoptosis in gastric cancer cells in vitro and […]

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COMPARATIVE HYPOGLYCEMIC ACTIVITY OF DIFFERENT FRACTIONS OF THYMUS SERPYLLUM L. IN ALLOXAN INDUCED DIABETIC RABBITS

Author: Alamgeer, Muhammad Naveed Mushtaq, Sajid Bashir, Ikram Ullah, Sabeha Karim, Muhammad Rashid, Muhammad Nasir Hayat Malik and Haroon-Ur-Rashid Publishing Date: 2016 E-ISSN: 1011-601X Volume: 29 Issue: 5 ABSTRACT: The aim of present study was to evaluate and compare the hypoglycemic activity of different solvents extracts of Thymus serpyllum in rabbits. Diabetes was induced with single intravenous injection of alloxan

COMPARATIVE HYPOGLYCEMIC ACTIVITY OF DIFFERENT FRACTIONS OF THYMUS SERPYLLUM L. IN ALLOXAN INDUCED DIABETIC RABBITS Read More »

SYNTHESIS, SPECTRAL ANALYSIS AND BIOLOGICAL EVALUATION OF NALKYL/ ARALKYL/ARYL-4-CHLOROBENZENESULFONAMIDE DERIVATIVES

Author: Aziz-ur-Rehman, Muhammad Athar Abbasi, Sabahat Zahra Siddiqui, Ayesha Mohyuddin, Sohail Nadeem and Syed Adnan Ali Shah Publishing Date: 2016 E-ISSN: 1011-601X Volume 29 Issue 5 ABSTRACT: New potent organic compounds were synthesized with an aim of good biological activities such as antibacterial and anti-enzymatic. Three series of sulfonamide derivatives were synthesized by treating N-alkyl/aryl substituted amines (2a-f) with 4-chlorobenzensulfonyl chloride

SYNTHESIS, SPECTRAL ANALYSIS AND BIOLOGICAL EVALUATION OF NALKYL/ ARALKYL/ARYL-4-CHLOROBENZENESULFONAMIDE DERIVATIVES Read More »

TLC PROFILING, NUTRITIONAL AND PHARMACOLOGICAL PROPERTIES OF SIBERIAN GINSENG (ELEUTHEROCOCCUS SENTICOSUS) CULTIVATED IN POLAND

Author: Daniel Załuski and Helena D Smolarz Publishing Date: 2016 E-ISSN: 1011-601X Volume: 29 Issue: 5 ABSTRACT: The chemical composition and pharmacological activity of E. senticosus cultivated in Poland were investigated. Studies included the assay of TPC and TFC, 2D-TLC identification of phenolic acids, HPTLC-detection of antioxidants, and antioxidative, antileukemic, anti-MMPs properties of E. senticosus. The ethanolic extracts from the

TLC PROFILING, NUTRITIONAL AND PHARMACOLOGICAL PROPERTIES OF SIBERIAN GINSENG (ELEUTHEROCOCCUS SENTICOSUS) CULTIVATED IN POLAND Read More »

EFFECT OF GABAB RECEPTOR ANTAGONISTS (CGP 35348 AND CGP 55845) ON SERUM INTERLEUKIN 6 AND 18 CONCENTRATIONS IN ALBINO MICE FOLLOWING NEONATAL HYPOXIA ISCHEMIA INSULT

Author: Quratulane Gillani, Muhammad Ali and Furhan Iqbal Publishing Date: 2016 E-ISSN: 1011-601X Volume: 29 Issue: 5 ABSTRACT: Interleukin (IL) 6 and 18 plays an important role in inflammatory response following hypoxia ischemia encephalopathy (HIE). Present study was designed to demonstrate the effect of two GABAB receptor antagonists (CGP 35348 and 55845), respectively, on the serum IL6 and IL 18

EFFECT OF GABAB RECEPTOR ANTAGONISTS (CGP 35348 AND CGP 55845) ON SERUM INTERLEUKIN 6 AND 18 CONCENTRATIONS IN ALBINO MICE FOLLOWING NEONATAL HYPOXIA ISCHEMIA INSULT Read More »