JatsTech

1011-601X_2016_29_3

Pakistan Journal of Pharmaceutical Sciences

UNRAVELING THE MOLECULAR MECHANISM GOVERNING THE TISSUE SPECIFIC EXPRESSION OF IFNΛR1

Author: Hashaam Akhtar, Ole Jensen Hamming, Syed Umer Jan, Samar Akhtar, Ewa Terczyn´ska-Dyla, Piotr Siupka, Adeena Shafique, Rune Hartmann and Hajra Sadia Publishing Date: 2016 E-ISSN: 1011-601X Volume: 29 Issue: 3 ABSTRACT: The functional receptor for type III interferons (IFNs) is a heterodimer of IFNLR1 and IL10R2. IFNLR1 is expressed in a highly tissue specific manner, with epithelial and liver […]

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SYNTHESIS OF 2-{(5-PHENYL-1,3,4-OXADIAZOL-2-YL)SULFANYL}-N-SUBSTITUTED ACETAMIDES AS POTENTIAL ANTIMICROBIAL AND HEMOLYTIC AGENTS

Author: Aziz-ur-Rehman, Muhammad Athar Abbasi, Sabahat Zahra Siddiqui, Irshad Ahmad, Muhammad Shahid and Zinayyera Subhani Publishing Date: 2016 E-ISSN: 1011-601X Volume: 29 Issue: 3 ABSTRACT: A new series of N-substituted derivatives of 2-{(5-phenyl-1,3,4-Oxadiazol-2-yl)sulfanyl}acetamides was synthesized. The synthesis was carried out by converting benzoic acid (1) into ethyl benzoate (2), benzohydrazide (3) and then 5-pheny-1,3,4-Oxadiazol-2-thiol (4) step by st0ep. The target

SYNTHESIS OF 2-{(5-PHENYL-1,3,4-OXADIAZOL-2-YL)SULFANYL}-N-SUBSTITUTED ACETAMIDES AS POTENTIAL ANTIMICROBIAL AND HEMOLYTIC AGENTS Read More »

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF SOME 5- METHYLPYRAZINE CARBOHYDRAZIDE BASED HYDRAZONES

Author: Mushtaq Ahmad, Shahid Hameed, Muhammad Nawaz Tahir, Muhammad Israr, Muhammad Anwar, Muhammad Abdullah Shah, Shad Ali Khan and Ghiasud Din Publishing Date: 2016 E-ISSN: 1011-601X Volume: 29 Issue: 3 ABSTRACT: Pyrazine carbohydrazide based hydrazones were synthesized starting from 5-methylpyrazine-2-carboxylic acid. The acid was first converted to its methyl ester, which on further treatment with hydrazine hydrate transformed to carbohydrazide.

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF SOME 5- METHYLPYRAZINE CARBOHYDRAZIDE BASED HYDRAZONES Read More »

PRELIMINARY PHYTOCHEMICAL SCREENING, ANTIBACTERIAL POTENTIAL AND GCMS ANALYSIS OF TWO MEDICINAL PLANT EXTRACTS

Author: Seerangaraj Vijayaram , Suruli Kannan, Konda Mani Saravanan , Seerangaraj, Vasantharaj Selvam Sathiyavimal and Palanisamy Senthilkumar P Publishing Date: 2016 E-ISSN: 1011-601X Volume: 29 Issue: 3 ABSTRACT: The presence study was aimed to catalyze the primary metabolites and their confirmation by using GC-MS analysis and antibacterial potential of leaf extract of two important medicinal plant viz., Eucalyptus and Azadirachta

PRELIMINARY PHYTOCHEMICAL SCREENING, ANTIBACTERIAL POTENTIAL AND GCMS ANALYSIS OF TWO MEDICINAL PLANT EXTRACTS Read More »

THE POSSIBLE COUNTERACTIVE EFFECT OF GOLD NANOPARTICLES AGAINST STREPTOZOTOCIN-INDUCED TYPE 1 DIABETES IN YOUNG MALE ALBINO RATS

Author: Manar E Selim, Awatif A Hendi and Ebtesam Alfallaj Publishing Date: 2016 E-ISSN: 1011-601X Volume: 29 Issue: 3 ABSTRACT: The current study was performed to study the effect of biologically synthesised gold nanoparticles (AuNPs) to control hyperglycaemic conditions in streptozotocin (STZ)-induced diabetic mice. In this study, the rats were divided into four groups: Group I normal control rats (non-diabetic,

THE POSSIBLE COUNTERACTIVE EFFECT OF GOLD NANOPARTICLES AGAINST STREPTOZOTOCIN-INDUCED TYPE 1 DIABETES IN YOUNG MALE ALBINO RATS Read More »