Author: Yavuz Bulent Kose, Gokalp Iscan, Fatih Goger , Betul Demirci and Ceren Elmacı

Publishing Date: 2017

E-ISSN: 1011-601X

Volume 30 Issue 6


In the present study hydrodistilled essential oil and total methanol extracts of Tanacetum argenteum subsp. flabellifolium have been evaluated for their antimicrobial and antioxidant effects. The chemical composition of the oil and the crude extract were determined by GC/FID, GC/MS and LC/DAD/ESI-MS systems respectively. β-thujone (47.1%), α-pinene (19.1%) and α-thujone (10.5%) were the main compounds of the essential oil while the 5-Ocaffeoylquinic acid, 1,5-O-dicaffeoylquinic acid, 4,5-O-dicaffeoylquinic acid were identified as flavonoid content of the crude extract. The oil and the methanol extract were demonstrated moderate antimicrobial effects (MIC range; 0,062-2,0 mg/mL) against 21 different pathogenic micro organism. Total phenolic content was determined as 63 mg GAE in g extract and the DPPH radical scavenging effect was determined as 0.16 mg/mL (IC50) and TEAC was determined as 0.21mMol.

Keywords: Tanacetum argenteum subsp. flabellifolium, essential oil, methanol extract, antimicrobial, antioxidant, GCFID, GC/MS, LC-MS/MS.

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