JatsTech

1011-601X_2017_30_5

Pakistan Journal of Pharmaceutical Sciences

SYNTHESIS, ENZYME INHIBITION AND MOLECULAR DOCKING STUDIES OF 1-ARYLSULFONYL-4-PHENYLPIPERAZINE DERIVATIVES

Author: Muhammad Athar Abbasi, Ambreen Anwar, Aziz-ur-Rehman, Sabahat Zahra Siddiqui, Kaniz Rubab, Syed Adnan Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: Heterocyclic molecules have been frequently investigated to possess various biological activities during the last few decades. The present work elaborates the synthesis and enzymatic inhibition potentials of a series of sulfonamides. A series of 1-arylsulfonyl-4-Phenylpiperazine (3a-n) geared […]

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IN VITRO ANTIOXIDANT AND ANTIBACTERIAL ACTIVITY OF VARIOUS EXTRACTS FROM EXOCARPS AND ENDOCARPS OF WALNUT

Author: Parastoo Zarghami Moghaddam, Ameneh Mohammadi, Peyman Feyzi , Peiman Alesheikh Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: Juglans regia seed has been used in traditional medicines as antimicrobial, antihelmintic and anti-diarrhoeal. In the present study, the antibacterial capabilities dichloromethane, ethyl acetate, methanol and aqueous extracts of endocarp and exocarp of walnut were determined against two Gram-positive bacteria

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ESSENTIAL MINERALS AND PHYTIC ACID IN LEGUMES WITH REFERENCE TO THEIR NUTRITIVE AND MEDICINAL PROPERTIES

Author: Salman Ahmed, Saad Bin Zafar Mahmood, Muhammad Mohtasheemul Hasan, Zafar Alam Mahmood Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: Three commonly used legumes, Macrotyloma uniflorum (Lam.) Verdc., Phaseolus lunatus Linn., and Phaseolus vulgaris Linn., were subjected to determine their minerals and phytic acid contents to correlate their nutritional and medicinal properties. To quantify essential minerals, atomic absorption

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SYNTHESIS OF 2-[(5-BENZYL-1,3,4-OXADIAZOLE-2YL)SULFANYL]-N-(ARYLATED/ARENYLATED) ACETAMIDES AS ANTIBACTERIAL AND ACETYL CHOLINESTERASE INHIBITORS

Author: Sabahat Zahra Siddiqui, Muhammad Athar Abbasi, Aziz-ur-Rehman, Muhammad Ashraf, Bushra Mirza, Hammad Ismail Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: The synthetic methodology is carried out in multistep which was initiated as phase I by utilizing Fischer esterification methodology of 2-phenylacetic acid (1) to ethyl-2-phenylacetate (2). The ester was reacted with hydrazine hydrate form 2-phenylacetohydrazide (3) which

SYNTHESIS OF 2-[(5-BENZYL-1,3,4-OXADIAZOLE-2YL)SULFANYL]-N-(ARYLATED/ARENYLATED) ACETAMIDES AS ANTIBACTERIAL AND ACETYL CHOLINESTERASE INHIBITORS Read More »

MOXIFLOXACIN REDUCES STENOTROPHOMONAS MALTOPHILIA ADHESION TO MOUSE INTESTINAL TRACT IN VITRO

Author: Ayaid Khadem Zgair, Jenan A Ghafil, Hala M. Radif, Shamim Naser Radhi, Mohammad H Hafiz, Shaymaa Fadhel Abbas Albaayit Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: Stenotrophomonas maltophilia is an important opportunistic pathogen that affects immunocompromised individuals. Viable bacterial count method was used to count the number of adhered bacteria. The current study showed the efficiency of

MOXIFLOXACIN REDUCES STENOTROPHOMONAS MALTOPHILIA ADHESION TO MOUSE INTESTINAL TRACT IN VITRO Read More »