JatsTech

1011-601X_2017_30_5

Pakistan Journal of Pharmaceutical Sciences

HISTOPATHOLOGICAL AND BIOCHEMICAL ASSESSMENT OF KIDNEY DAMAGE IN ALBINO WISTAR RATS TREATED WITH CYTOTOXIC PLATINUM COMPOUNDS IN COMBINATION WITH 5-FU

Author: Nusrat Bano, Rahila Ikram Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: Kidney cells damage and subsequent renal adverse effects with oxaliplatin are less reported phenomena, whereas cisplatin (CDDP, first generation platinum compound) has therapeutic limitations due to renal toxicity. This experimental study reports oxaliplatin (third generation platinum compound) induced direct damage in rat kidney tissues and alterations […]

HISTOPATHOLOGICAL AND BIOCHEMICAL ASSESSMENT OF KIDNEY DAMAGE IN ALBINO WISTAR RATS TREATED WITH CYTOTOXIC PLATINUM COMPOUNDS IN COMBINATION WITH 5-FU Read More »

DEVELOPMENT AND VALIDATION OF HPLC METHOD FOR THE DETERMINATION OF CEFPODOXIME PROXETIL IN HUMAN PLASMA

Author: Lubna Bashir, Muhammad Harris Shoaib, Shazia Naz, Rabia Ismail Yousuf, Sabahat Jabeen, Fozia Israr, Fahad Siddiqui Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: A new, simple, accurate, precise and specific method has been developed for the analysis of Cefpodoxime Proxetil in human plasma. The proposed method was developed and validated with the aim to be used in

DEVELOPMENT AND VALIDATION OF HPLC METHOD FOR THE DETERMINATION OF CEFPODOXIME PROXETIL IN HUMAN PLASMA Read More »

CHANGES IN BLOOD PRESSURE, VASCULAR REACTIVITY AND INFLAMMATORY BIOMARKERS FOLLOWING CONSUMPTION OF HEATED CORN OIL

Author: Srijit Das, Mohamed Afiq Hamsi, Yusof Kamisah, Hj Mohd Saad Qodriyah, Faizah Othman, Adel Emran, Zaiton Zakaria , Kamsiah Jaarin Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: Consumption of corn oil for cooking purpose is gaining popularity. The present study examined the effect of heated corn oil on blood pressure and its possible mechanism in experimental rats.

CHANGES IN BLOOD PRESSURE, VASCULAR REACTIVITY AND INFLAMMATORY BIOMARKERS FOLLOWING CONSUMPTION OF HEATED CORN OIL Read More »

SYNTHESIS OF SECONDARY METABOLITES BY CLADOSPORIUM RESINAE (NRL-6437) UNDER DIFFERENT GROWTH MEDIA AND CHEMICAL INDUCERS AND THEIR PHARMACEUTICAL ACTIVITY

Author: Abid Ali Khan, Nafees Bacha, Bashir Ahmad, Jehan Bakht, Ghosia Lutfullah, Johar Ali Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: The role of different growth media and chemical enhancer on synthesis of secondary metabolites Cladosporium resinae (NRL-6437) was investigated for their in vitro biological activities. Cladosporium resinae (NRL- 6437) were grown in various nutrient media (Czapeak-dox Broth

SYNTHESIS OF SECONDARY METABOLITES BY CLADOSPORIUM RESINAE (NRL-6437) UNDER DIFFERENT GROWTH MEDIA AND CHEMICAL INDUCERS AND THEIR PHARMACEUTICAL ACTIVITY Read More »

EVALUATION OF ANTIOXIDANT ACTIVITY OF LEAVES AND FRUITS EXTRACTS OF FIVE MEDICINAL PLANTS

Author: Iram Fatima, Tanveer Hussain, Muhammad Rafay, Muhammad Akram, Sabahat Bano, Sammia Shabbir Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 5 ABSTRACT: Antioxidants acts as a defense mechanism that protects against oxidative damage caused by free radicals produced in the body. Medicinal plants are preferably used for various diseases in many countries. The studies were conducted to determine the antioxidant

EVALUATION OF ANTIOXIDANT ACTIVITY OF LEAVES AND FRUITS EXTRACTS OF FIVE MEDICINAL PLANTS Read More »