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1011-601X_2017_30_4

Pakistan Journal of Pharmaceutical Sciences

EFFECTS OF TWO FUNCTIONALLY IMPORTANT SLCO1B1 GENE POLYMORPHISMS ON PHARMACOKINETICS OF ATORVASTATIN

Author: Tausif Ahmed Rajput, Abdul Khaliq Naveed, Zia-Ur-Rehman Farooqi, Shakir Khan Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 4 ABSTRACT: Organic anion transporter polypeptide 1B1 (OATP1B1) encoded by (SLCO1B1) gene, an uptake transporter involved in the transport of drugs and endogenous compounds and located in hepatocyte sinusoidal membrane. Objective of study was to investigate the effects of two functionally significant […]

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IN VITRO ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF DIFFERENT SOLVENT EXTRACTED SAMPLES FROM THE STEM OF EUPHORBIA HELISCOPIA

Author: Jehan Bakht, Faiza, Mohammad Shafi, Arshad Iqbal Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 4 ABSTRACT: This paper presents the anti-microbial potentials of methanol, ethyl acetate, n-hexane, butanol and water extracted samples from the stem of Euphorbia heliscopia against S. aureus (Gram positive), B. subtilis (Gram positive), P. aeruginosa (Gram negative), K. pneumonia (Gram negative), E. coli (Gram negative),

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THE PRACTICE OF SELF-MEDICATION AMONG PAKISTANI UNIVERSITY STUDENTS

Author: Mamoona Mushtaq, Saleem Gul, Fauzia Naz Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 4 ABSTRACT: Self-medication refers to the selection and use of medicines without prescription by an individuals’ personal responsibility as a cure of self-identified disease. Although its rationale, type and extent may different from culture to culture, it is globally prevalent practice. In Pakistan no research is

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IN VITRO IMMUNE POTENTIALS OF A WATER-SOLUBLE POLYSACCHARIDE EXTRACT FROM DIOSCOREA OPPOSITA PLANTED IN HENAN PROVINCE, CHINA

Author: Li-Xin Hao, Xin-Huai Zhao Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 4 ABSTRACT: Dioscorea opposita is an edible and medicinal plant available in many areas of China. This study aimed to assess in vitro immune potentials of a water-soluble polysaccharide extract from D. opposita planted in Henan Province, China. In vitro effects of the extract on three immune cells

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PHENOLICS FOR SKIN PHOTO-AGING

Author: Atif Ali Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 4 ABSTRACT: Photo-aging is one of the foremost problems caused by generation of reactive oxygen species when skin is exposed on UV irradiation. In view of that, generation of reactive oxygen species intermingle with proteins, DNA, saccharides and fatty acids triggering oxidative mutilation and effects are in the appearance of

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