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1011-601X_2017_30_2

Pakistan Journal of Pharmaceutical Sciences

HYPOURICEMIC AND NEPHROPROTECTIVE EFFECTS OF TOTAL FLAVONOIDS FROM THE RESIDUE OF SUPERCRITICAL CO2 EXTRACTION OF HUMULUS LUPULUS IN POTASSIUM OXONATE-INDUCED MICE

Author: Zhen Jing Li, Zhuan Li, Xiao Ying Dong, Lai Feng Lu and Chang Lu Wang Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 2 ABSTRACT: Total flavonoids of Humulus lupulus (TFHL) were prepared using ethanol extraction, liquid-liquid partition and purification with polyamide resin. Different dose of TFHL were orally administered to normal and hyperuricemic mice for 7 days. The xanthine […]

HYPOURICEMIC AND NEPHROPROTECTIVE EFFECTS OF TOTAL FLAVONOIDS FROM THE RESIDUE OF SUPERCRITICAL CO2 EXTRACTION OF HUMULUS LUPULUS IN POTASSIUM OXONATE-INDUCED MICE Read More »

RENAL CLEARANCE AND URINARY EXCRETION OF OMEPRAZOLE IN HEALTHY FEMALE VOLUNTEERS IN PAKISTAN

Author: Nazia Qadir, Tanweer Khaliq, Rai Altaf Hussain, Ghulam Abbas Shah, Sadia Asharaf, Ahmad Raza and Nadia Noor Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 2 ABSTRACT: Omeprazole is a widely prescribed proton pump inhibitor to treat various gastric acid hyper secretion disorders. The present study was designed to evaluate the renal clearance and urinary excretion of omeprazole in eight

RENAL CLEARANCE AND URINARY EXCRETION OF OMEPRAZOLE IN HEALTHY FEMALE VOLUNTEERS IN PAKISTAN Read More »

HEPATOPROTECTIVE EVALUATION OF AQUEOUS-ETHANOLIC EXTRACT OF CAPPARIS DECIDUA (STEMS) IN PARACETAMOL INDUCED HEPATOTOXICITY IN EXPERIMENTAL RABBITS

Author: Jalil Ur Rehman, Naveed Akhtar, Hafiz Muhammad Asif, Sabira Sultana and Mukhtiar Ahmad Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 2 ABSTRACT: Liver diseases are the most common ailment all over the world mostly caused by viruses, toxic chemicals, excessive intake of alcohol, high doses of paracetamol, carbon tetrachloride, chemotherapeutic agents and peroxides oil, etc. There is a great

HEPATOPROTECTIVE EVALUATION OF AQUEOUS-ETHANOLIC EXTRACT OF CAPPARIS DECIDUA (STEMS) IN PARACETAMOL INDUCED HEPATOTOXICITY IN EXPERIMENTAL RABBITS Read More »

3-(4-CHLOROPHENYL)-[1, 2, 3] OXADIAZOL-3-IUM-5-OLATE AND ITS 4-FORMYL ANALOG-ULTRASOUND ASSISTED SYNTHESIS AND IN-VITRO ANTICANCER EVALUATION AGAINST HUMAN TUMOR CELL LINES

Author: Sachin K Bhosale, Shreenivas R Deshpande and Rajendra D Wagh Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 2 ABSTRACT: The title compound, 3-(4-chlorophenyl)-4-formyl-[1, 2, 3] oxadiazol-3-ium-5-olate 5 was synthesized under ultrasonication by formylation of 3-(4-chlorophenyl)-[1, 2, 3] oxadiazol-3-ium-5-olate 4 and characterized by spectral studies. The ultrasonic method of synthesis was found to be simple, ecofriendly, economical, reduces reaction time

3-(4-CHLOROPHENYL)-[1, 2, 3] OXADIAZOL-3-IUM-5-OLATE AND ITS 4-FORMYL ANALOG-ULTRASOUND ASSISTED SYNTHESIS AND IN-VITRO ANTICANCER EVALUATION AGAINST HUMAN TUMOR CELL LINES Read More »

CYTOTOXICITY AND CHROMOSOMAL ABERRATIONS INDUCED BY METHANOLIC EXTRACT OF CUSCUTA REFLEXA AND ITS PURE COMPOUNDS ON MERISTEMATIC CELLS OF ALLIUM SPECIES

Author: Syeda Roohina Ali, Sayedul Haque, Mudassar, Muhammad Ali Versiani, Shaheen Faizi and Ahsana Dar Farooq Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 2 ABSTRACT: Cuscuta reflexa (Convolvulaceae), is commonly known as amarbel or akashbel. In Bangladesh and Nepal some of the tribes use C. reflexa against edema, body ache, cancer, skin infections and liver disorders. Despite its traditional uses

CYTOTOXICITY AND CHROMOSOMAL ABERRATIONS INDUCED BY METHANOLIC EXTRACT OF CUSCUTA REFLEXA AND ITS PURE COMPOUNDS ON MERISTEMATIC CELLS OF ALLIUM SPECIES Read More »