JatsTech

1011-601X_2017_30_2

Pakistan Journal of Pharmaceutical Sciences

EFFECT OF VKORC1 AND CYP2C9 POLYMORPHISMS ON WARFARIN DOSE REQUIREMENT IN BANGLADESHI POPULATION

Author: Zahid Sadek Chowdhury, Farah Shahjin, Farhana Akter, Maizbha Uddin Ahmed, Mohammad Safiqul Islam, Muhammad Shahdaat Bin Sayeed, Reazul Islam and Abul Hasnat Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 2 ABSTRACT: Warfarin, an oral anticoagulant is one of the most widely prescribed drugs in modern medicine. Large interindividuals variability due to age, gender, diet, concurrent drug interactions and variations […]

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LONICERA QUINQUELOCULARIS: A RICH SOURCE OF ANTIOXIDANT FOR PROTECTION AGAINST CHRONIC DISEASES

Author: Sabahat Zahra Siddiqui, Hina Saleem, Muhammad Athar Abbasi, Aziz-ur-Rehman and Muhammad Ajaib Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 2 ABSTRACT: The purpose of the research work was to examine the in vitro antioxidant activity of the different aqueous and organic fractions of Lonicera quinquelocularis Hardwicke. The methanol extract was dissolved in distilled water and fractioned with n-hexane, chloroform,

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FORMULATION AND IN VITRO EVALUATION OF SUSTAINED RELEASE MATRIX TABLETS USING CROSS-LINKED NATURAL GUM

Author: Qurrat Ul Ain Jamil, Muhammad Irfan Masood, Muhammad Nauman Jamil, Imran Masood and Shahid Muhammad Iqbal Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 2 ABSTRACT: Polysaccharide gums because of their biocompatibility, biodegradability and non-immunogenic properties are considered as the best choice for preparing sustained release tablets as compared to their synthetic counterpart. The cross linking of natural gums in

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BUSPIRONE ATTENUATES METHYLPHENIDATE-INDUCED GROWTH INHIBITION

Author: Nausheen Alam and Rahila Najam Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 2 ABSTRACT: Methylphenidate is effective in the treatment of attention deficit hyperactivity disorder (ADHD) in children and adults, but its long term use can cause potential adverse effect on growth rate and variable effects on appetite. Previous studies have shown that long term administration of psychostimulant drugs

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PREVENTION OF CCL4 INDUCED HYPOGONADISM WITH RAPHANUS SATIVUS SEEDS IN RAT

Author: Farhana Tabassum and Muhammad Rashid Khan Publishing Date: 2017 E-ISSN: 1011-601X Volume 30 Issue 2 ABSTRACT: Raphanus sativus seeds are used as condiment and to treat hypogonadism, various ailments of liver and kidneys. The aim of this study was to evaluate the potential protective effects of methanol extract of R. sativus seeds (RSME) against hypogonadism induced with carbon tetrachloride (CCl4)

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