JatsTech

1011-601X_2016_29_6

Pakistan Journal of Pharmaceutical Sciences

SYNTHESIS AND SCREENING OF SOME NEW N-ALKYL/ARALKYL-N-(3,4- METHYLENEDIOXYBENZYL)-4-SUBSTITUTED BENZENESULFONAMIDES AS POTENTIAL ANTIBACTERIAL AGENTS

Author: Aziz-ur-Rehman, Asia Siddiqa, Muhammad Athar Abbasi, Sabahat Zahra Siddiqui and Shahid Rasool Publishing Date: 2016 E-ISSN: 1011-601X Volume 29 Issue 6 ABSTRACT: The various p-substituted benzenesulfonyl chlorides (2a-e) were treated with (3,4-methylenedioxy) benzylamine (1) in the presence of aqueous Na2CO3 solution to synthesize N-(3,4-methylenedioxybenzyl)-4- substitutedbenzenesulfonamides (3a-e). The synthesized molecules were further converted into corresponding Nethyl/ benzyl/4-flourobenzyl-N-(3,4-methylenedioxybenzyl)-4-substitutedbenzenesulfonamides (7a-e, 8a-e, 9a-e) on […]

SYNTHESIS AND SCREENING OF SOME NEW N-ALKYL/ARALKYL-N-(3,4- METHYLENEDIOXYBENZYL)-4-SUBSTITUTED BENZENESULFONAMIDES AS POTENTIAL ANTIBACTERIAL AGENTS Read More »

ANTIBACTERIAL ACTIVITY OF A PEPTIDE DERIVED FROM HIV-1 MN STRAIN GP41 ENVELOPE GLYCOPROTEIN AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS

Author: Sin-Yeang Teow and Syed Atif AliD Publishing Date: 2016 E-ISSN: 1011-601X Volume 29 Issue 6 ABSTRACT: Peptides derived from HIV-1 transmembrane proteins have been extensively studied for antimicrobial activities, and they are known as antimicrobial peptides (AMPs). These AMPs have also been reported to potently combat the drug-resistant microbes. In this study, we demonstrated that peptide #6383 originated from HIV-1

ANTIBACTERIAL ACTIVITY OF A PEPTIDE DERIVED FROM HIV-1 MN STRAIN GP41 ENVELOPE GLYCOPROTEIN AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS Read More »

EVALUATION OF THE SCOLICIDAL EFFECTS OF NECTAROSCORDUM TRIPEDALE EXTRACT AND ITS ACUTE TOXICITY IN MICE MODEL

Author: Hossein Mahmoudvand, Behrouz Ezatpour, Marzieh Rashidipour, Seyed Reza Mirbadie and Hormoz Mahmoudvand Publishing Date: 2016 E-ISSN: 1011-601X Volume 29 Issue 6 ABSTRACT: Current scolicidal agents, which have been used for inactivation of protoscoleces during hydatid cyst surgery are associated with adverse side effects. This study aims to evaluate the in vitro scolicidal effects of Nectaroscordum tripedale L. leave extract against

EVALUATION OF THE SCOLICIDAL EFFECTS OF NECTAROSCORDUM TRIPEDALE EXTRACT AND ITS ACUTE TOXICITY IN MICE MODEL Read More »

ANTIUROLITHIATIC PLANTS: FORMULATIONS USED IN DIFFERENT COUNTRIES AND CULTURES

Author: Salman Ahmed1, Muhammad Mohtasheemul Hasan1* and Zafar Alam Mahmood2 Publishing Date: 2016 E-ISSN: 1011-601X Volume 29 Issue 6 ABSTRACT: About 12% of world population is affected by different forms of urolithiasis in which the recurrence rate in female is 47-60% and in male is 70-80%. According to WHO 75% people rely on traditional medicines for the prevention and cure of

ANTIUROLITHIATIC PLANTS: FORMULATIONS USED IN DIFFERENT COUNTRIES AND CULTURES Read More »