SYNTHESIS AND SCREENING OF SOME NEW N-ALKYL/ARALKYL-N-(3,4- METHYLENEDIOXYBENZYL)-4-SUBSTITUTED BENZENESULFONAMIDES AS POTENTIAL ANTIBACTERIAL AGENTS
Author: Aziz-ur-Rehman, Asia Siddiqa, Muhammad Athar Abbasi, Sabahat Zahra Siddiqui and Shahid Rasool Publishing Date: 2016 E-ISSN: 1011-601X Volume 29 Issue 6 ABSTRACT: The various p-substituted benzenesulfonyl chlorides (2a-e) were treated with (3,4-methylenedioxy) benzylamine (1) in the presence of aqueous Na2CO3 solution to synthesize N-(3,4-methylenedioxybenzyl)-4- substitutedbenzenesulfonamides (3a-e). The synthesized molecules were further converted into corresponding Nethyl/ benzyl/4-flourobenzyl-N-(3,4-methylenedioxybenzyl)-4-substitutedbenzenesulfonamides (7a-e, 8a-e, 9a-e) on […]