JatsTech

1011-601X_2016_29_5

Pakistan Journal of Pharmaceutical Sciences

SYNTHESIS, ANTIBACTERIAL AND ANTIFUNGAL POSSESSION OF AMINO ACIDS CONTAINING SULFONAMIDE MOIETIES

Author: Muhammad Abdul Qadir, Mahmood Ahmed and Anum Khaleeq Publishing Date: 2016 E-ISSN: 1011-601X Volume: 29 Issue: 5 ABSTRACT: Sulfonamides were developed by the simple reaction of amino acid with p-toluenesulfonyl chloride and structures of the new products (2a, 2b and 2c) were confirmed by elemental and spectral analysis (FT-IR, 1HNMR and13CNMR). In vitro, developed compounds were screened for their […]

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EFFECTS OF DEXMEDETOMIDINE ON THE DEFORMABILITY OF ERYTHROCYTE IN PATIENTS WITH LAPAROSCOPIC CHOLECYSTECTOMY

Author: Xming Yang, Jie Xie, Jun Liu and Tao Wang Publishing Date: 2016 E-ISSN: 1011-601X Volume: 29 Issue: 5 ABSTRACT: This study aims to study the impact of dexmedetomidine on the deformability of erythrocyte in patients with laparoscopic cholecystectomy. 40 patients scheduled for laparoscopic cholecystectomy were randomly divided into 2 groups: Dexmedetomidine group (0.5μg/kg loading within 10 min and 0.5μg·kg-1·h-1maintenance

EFFECTS OF DEXMEDETOMIDINE ON THE DEFORMABILITY OF ERYTHROCYTE IN PATIENTS WITH LAPAROSCOPIC CHOLECYSTECTOMY Read More »

RAUWOLFIA SERPENTINA IMPROVES ALTERED GLUCOSE AND LIPID HOMEOSTASIS IN FRUCTOSE-INDUCED TYPE 2 DIABETIC MICE

Author: Muhammad Bilal Azmi and Shamim A Qureshi Publishing Date: 2016 E-ISSN: 1011-601X Volume: 29 Issue: 5 ABSTRACT: Rauwolfia serpentina is well-reported in traditional medicines for the treatment of hypertensive and neurological disorders. However, its antidiabetic potential has been currently described in both alloxan-treated and normoglycemic mice. Present effort was carried out to investigate the effect of methanol root extract

RAUWOLFIA SERPENTINA IMPROVES ALTERED GLUCOSE AND LIPID HOMEOSTASIS IN FRUCTOSE-INDUCED TYPE 2 DIABETIC MICE Read More »

EFFECT OF CALCIUM HYPOCHLORITE AND CHLORAMINE ON BLOOD BIOCHEMISTRY AND SODIUM PENTOBARBITAL INDUCED SLEEPING TIME IN MICE

Author: Sidra Ishaq, Muhammad Adil Rasheed, Muhammad Ashraf, Imran Altaf, Saima Rehmat and Ghulam Fatima Publishing Date: 2016 E-ISSN: 1011-601X Volume: 29 Issue: 5 ABSTRACT: Disinfectants are chemical agents used to eradicate, deactivate or kill microorganisms. Chemical disinfectants especially chlorine compound are extensively used for water sanitization. Among these calcium hypochlorite and chloramines are commonly used now a day. Large

EFFECT OF CALCIUM HYPOCHLORITE AND CHLORAMINE ON BLOOD BIOCHEMISTRY AND SODIUM PENTOBARBITAL INDUCED SLEEPING TIME IN MICE Read More »

DOES PORPHYRIN SUPPRES THE APOPTOTIC AND NECROTIC EFFECTS OF BOVINE HERPES VIRUS TYPE-1(BOHV-1) AND HERPES SIMPLEX VIRUS TYPE-1(HSV-1)?

Author: Beyza Yavuz and Zafer Yazici Publishing Date: 2016 E-ISSN: 1011-601X Volume: 29 Issue: 5 ABSTRACT: In this study, antiviral effect of porphyrin was investigated. Cooper strain of Bovine Herpes Virus type 1(BoHV-1) and Kos strain of Herpes Simplex Virus type-1 (HSV-1) were used to determine the potential of porphyrins to inhibit infection in vitro (with morphological and cytopathological criteria).

DOES PORPHYRIN SUPPRES THE APOPTOTIC AND NECROTIC EFFECTS OF BOVINE HERPES VIRUS TYPE-1(BOHV-1) AND HERPES SIMPLEX VIRUS TYPE-1(HSV-1)? Read More »