FORMULATION AND OPTIMIZATION OF FLOATING MATRIX TABLETS OF CLARITHROMYCIN USING SIMPLEX LATTICE DESIGN
Author: Inderbir Singh and Vikrant Saini Publishing Date: 2016 E-ISSN: 1011-601X Volume: 29 Issue: 2 ABSTRACT: The purpose of the present study was to prepare floating matrix tablets of clarithromycin employing simplex lattice design. Hydroxypropyl methylcellulose (HPMC) and Ethyl Cellulose (EC) were used as matrix forming agents; sodium bicarbonate and citric acid as effervescence producing agents. Simplex lattice design was […]