Author: Muhammad Taher, Mohamed Zaffar Ali Mohamed Amiroudine, Juliana Md Jaffri, Mohamad Shahreen Amri, Deny Susanti, Shafida Abd Hamid, Mohamad Fazlin Rezali, Choudhury Mahmood Hassan, Roger W Read, Qamar Uddin Ahmed, Farediah Ahmad

Publishing Date: 2017

E-ISSN: 1011-601X

Volume 30 Issue 4


A new naturally occurring dibenzylbutyrolactone lignan named isocubebinic ether has been isolated from Knema patentinervia. The structure was established by spectroscopic methods, which include Ultraviolet, Infrared, Nuclear Magnetic Resonance and Mass Spectrometry. The compound showed activity in the stimulation of glucose uptake by 3T3-L1 adipocytes.

Keywords: Knema patentinervia, lignan, glucose uptake, 3T3-L1 adipocytes.

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